One of The Top Herbal Remedies for Allergies and Sinus

According to research, seasonal allergies have a lower total symptom score when inflammation is reduced. Regulating the immune system is shown to produce positive results when considered in the treatment plan for allergies. (1)


People often attempt to maintain immune health and overall wellness by undergoing seasonal detoxes. However, when it comes to seasonal detoxes, people who suffer from allergies and immune manifestations should be very cautious (2). The necessary detox may cause moderate to severe allergic symptoms, which are usually classified as a "healing crisis". The mobilization of toxins and the release of fatty acids into the bloodstream due to fat breakdown might be the trigger. This mobilization of toxins may affect the health of virtually all body organs.

Black Seed is a Top Herbal Remedy for Allergies and Sinus

Preforming an Allergy Detox

A holistic sinus and allergy detox keeps in mind the state of delicate detox organs like the liver and the kidney(3, 4). Taking steps to calm the immune system, maintain a healthy anti-oxidant load, and shield the organs from toxins may all help to make the procedure smoother and more manageable.


Symptoms that may improve with healthy detoxes include chronic sinusitis and over-irritation of the delicate mucus membranes. This may result in fewer symptoms of allergies, clearer nasal passages, and less chance of hay fever upon future allergen exposure. Those symptoms are much more likely to resolve if organs like the lung, heart, blood vessels, and liver are taken into account.



Common Effective Remedies You Never Think of as Detox:

  • Neti Pot: Gets rid of a runny nose by clearing away toxins and allergens in the nasal passages

  • Essential Oils: Stimulate the body's immune response to clean up accumulated allergins and inflammatory markers

  • Vitamin C: Clears the oxidation that is caused by toxins, microorganisms, and allergins

  • Saline Solution: Helps to act as a magnet that draws out impurities

  • Allergy Medications: Assist the body a detoxing (or removing) allergic chemicals like histamine by lowing their production or inhibiting their channels which gives the body the chance to catch up and clear passageways

  • Nasal Spray: May function like the neti pot or like allergy medications

  • Stinging Nettle: Urtica dioica or nettle tea is a plant that supports detox pathways

  • Rosmarinic Acid: Helps to decrease allergic immunoglobulins by breaking them down

  • Eucalyptus Oil: Helps to breakdown allergic and inflammatory chemicals

Black seed for sinuses

Science Behind Detoxification

Detoxing is the process of removing accumulated byproducts from the body. It is a natural process in the liver, kidneys, lungs, and skin. The liver is one of the most important detox organs in our body. It filters out toxins from our blood and sends them to be excreted by other organs like the kidneys and lungs. The liver also produces bile, which helps break down fats and cholesterol in our diet. The kidneys are another vital organ for detoxification because they filter out waste products from our blood and send them to be excreted by urination or some, through sweat. (5,6)


Some organs have their pathways for detox. The brain, for example, uses the time spent sleeping to break down toxic metabolites. Likewise, the lungs detoxify the body from gases. Toxic gases are expelled through respiration. (7,8)

Science of Seasonal Allergies (Link to Detox)

Detox aggravation:

  • Mobilization of toxins in the blood to be eliminated

  • Interaction with organ-function

  • Feeling tired or sluggish 

  • Increase in oxidation

  • Increase in allergies and intolerances 

When healthy weight loss or fasting autophagy takes place:

  • The body activates the process of breaking down to rebuild

  • The body gets rid of cellular waste

Challenges of weight loss:

  • Fats dumped into the blood

  • Blood sugar fluctuations in blood glucose

  • Toxins built into the composition of the body are mobilized

When we start a seasonal detox, we are ultimately looking to mobilize toxins (8,9,10). When freed, those toxins are dumped into the bloodstream. Factors that may make detox more stressful include toxicity load, toxin type, and organ function. 


The mobilization of toxins from tissues causes an overload on our organs and can worsen symptoms such as fatigue and unregulated immunity. Remember that the toxins can disrupt organ function, alter cellular signalling, and even oversensitized the immune system due to their inflammatory nature. For some individuals, the process leads to a worsening of symptoms. (10).


Common Treatment Options For Allergies:

  • Prescription medications

  • Over-the-counter medications

  • Natural remedies like essential oils, neti-pots or saline nasal irrigation

  • Dietary supplements (a natural antihistamine)

  • Allergy shots

  • The utilization of air purifiers

One of The Top Herbal Remedies for Allergies and Sinus

Scrambling through Middle Eastern classic texts of medicine reveals that the benefits of black seed oil are endless. It has been used for centuries in the Middle East and India as a natural remedy for almost every ailment. As one of the most vastly studied botanicals, scientific evidence points towards the true medicinal versatility of the botanical. (11,12)

Scientific Evidence Supporting Black Seed Oil in Human Clinical Trials

Black Seed Oil for Lung Health

The respiratory benefits of black seed oil have been well studied in clinical trials. Though many of the respiratory benefits of black seed oil are linked to the immune balancing properties of the plant. According to the ancient doctors of the Middle East, it’s the intense flavour that heals the lungs. (13)


When it comes to the lung as an organ, some studies show improvement in lung function and an enhancement in the filling and stretching of the lung. Other studies link the lung benefits to a decrease in inflammation, leading to a decrease in the thickness of secretion and thus better oxygen exchange. (13)


Black seed is thought to reduce nasal congestion by inhibiting the release of histamine. Such a characteristic makes it one of the best herbal remedies for allergy relief. The oil of the black seed is a bronchodilator that can help with asthma symptoms. It has also been linked to an improved post-nasal drip, sore throat, and allergic rhinitis. (13,14,15)


Common Symptoms of Allergies:

  • Itchy eyes

  • Watery eyes

  • Chronic sinus infections

  • Symptoms worsen during the allergy season

  • Puffy nose

  • Allergic asthma

Black seed for lungs

Black Seed Oil for Liver Detox

Black seed oil is a natural product that can help improve liver function and reduce the effects of liver toxins. Due to its flavour and use for blood sugar irregularities, the plant has been used for centuries as a hepatoprotective agent in traditional medicine. In addition, it has been shown to have potent anti-inflammatory properties, which can help reduce the effects of liver toxins by reducing inflammation in the body. (16,17)


The anti-inflammatory properties also help improve liver function in hepatitis and other tissue-injuring diseases. It can also help prevent liver damage by decreasing the number of fat deposits that accumulate around the organ. (16)


Several studies on the detox potential of black seed oil demonstrate that thymoquinone is protective against natural toxins like aflatoxin (common in fungus-infected peanuts). It also appears to protect the liver from hepatotoxicity due to metals, antibiotics, and chemical agents (like ethanol). The protection offered by thymoquinone expands from hepatoprotection to nephroprotection, cardioprotection, gastrointestinal protection, and pulmonary protection. (18)


The mechanism of protection is thought to be multifactorial and encompasses:

  • Inhibition of free radical formation

  • Restoration of the antioxidant system

  • Preservation of the activity of antioxidant enzymes

  • Anti-inflammatory and anti-angiogenic activity

  • Lipid peroxidation protection

  • Mitochondrial health enhancement

  • Anti-apoptotic (also signals apoptosis for unwanted growths)

  • Suppression of renal binding of oxidants

  • Regulation of organ-specific immune mediators

  • Enhancement of energy production (18)

Black seed for liver health

Black Seed Oil for Immune Conditions

Studies demonstrate good efficacy for using black seed oil to protect the body against an over-active immune system, inflammation, and autoimmune diseases like celiac disease.


For those suffering from gastrointestinal sensitivity, studies demonstrate an improvement in both gut and skin symptoms when it comes to celiac disease. Additionally, other studies show a tangible change in inflammatory markers. (19,20)

Upper Respiratory Effects

  • Improves allergic rhinitis
  • Improves sore throat 

  • Improves post-nasal drip

Lower Respiratory Effects

  • Improves asthma symptoms

  • Bronchodilator

  • It improves allergic symptoms

Cardiovascular Support

  • It reduces cholesterol and blood pressure

  • Improves fat profile

Hepatoprotective Effects

  • Reduces the effects of liver toxins

  • It improves liver function for hepatitis patients

Metabolic Effects

  • It promotes weight regulation

  • Improves sperm parameters

Neurological Effects

  • Improves epilepsy

  • Improves memory

  • It helps with opioid withdrawal

Immune Effects

  • It improves auto-immune disease symptoms

Dermatological Effects

  • It decreases vitiligo lesions

  • Relieves eczema

  • It improves celiac disease-related skin manifestations

Gastric Effects

  • Improves stomach ulcer symptoms

  • Reduces dyspepsia

Intestinal Effects

  • Anti-parasitic

  • Improves Celiac symptoms

"Black seed oil is a natural way to detox the body. It can help with liver health, and it can also support weight loss"

Black Seed for Detox Conclusions

Black seed oil is one of the top herbal remedies for allergies and sinus. Itcan help with seasonal allergies by supporting a healthy detox, decreasing inflammation, balancing the immune system, decreasing immune markers, and calming over-reactive immunity. It also acts as an immune anti-oxidant.


Sometimes the much-needed detox can trigger moderate to severe allergy symptoms and immune manifestations. The trigger may be linked to the toxins’ mobilization and the fatty acids that enter the blood due to fat breakdown. 


Calming the immune system, ensuring a healthy anti-oxidant load and protecting the organs from toxins may significantly help make the process smoother and tolerable for an extended period. Paying extra attention to the designated detox organs of the body can dramatically support a healthy and impactful detox!

Dr Jewel Alfoure  – Naturopathic Doctor at Enerex Botanicals

DR JEWEL ALFOURE, ND

Dr Jewel is a dedicated Doctor of Naturopathic Medicine who is known for her unwavering passion and commitment to delivering evidence-based natural medicine with a compassionate touch

Visit Dr Jewel's Education Hub

Article References:


  1. Maleki SJ, Crespo JF, Cabanillas B. Anti-inflammatory effects of flavonoids. Food Chemistry. 2019 Nov 30;299:125124.

  2. Williams X. Liver Detox Plan: The revolutionary way to cleanse and revive your body. Random House; 2012 Jun 30.

  3. Le Floc'h N, Melchior D, Obled C. Modifications of protein and amino acid metabolism during inflammation and immune system activation. Livestock Production Science. 2004 Apr 1;87(1):37-45.

  4. Kieffer DA, Martin RJ, Adams SH. Impact of dietary fibers on nutrient management and detoxification organs: gut, liver, and kidneys. Advances in Nutrition. 2016 Nov;7(6):1111-21.

  5. Cutler EW. Live Free from Asthma and Allergies: Use the BioSET System to Detoxify and Desensitize Your Body. Celestial Arts; 2007.

  6. Grant DM. Detoxification pathways in the liver. Journal of inherited metabolic disease. 1991:421-30.

  7. Cong L, Mirosa M, Kaye-Blake W, Bremer P. Immune-boosting functional foods: A potential remedy for Chinese consumers living under polluted air. Business and Management Studies. 2020.

  8. Smith-Sivertsen, T., Diaz, E., Pope, D., Lie, R.T., Diaz, A., McCracken, J., Bakke, P., Arana, B., Smith, K.R. and Bruce, N., 2009. Effect of reducing indoor air pollution on women's respiratory symptoms and lung function: the RESPIRE Randomized Trial, Guatemala. American journal of epidemiology, 170(2), pp.211-220.

  9. Lim YH, Kim H, Kim JH, Bae S, Park HY, Hong YC. Air pollution and symptoms of depression in elderly adults. Environmental health perspectives. 2012 Jul;120(7):1023-8.

  10. Dey T, Gogoi K, Unni B, Bharadwaz M, Kalita M, Ozah D, Kalita M, Kalita J, Baruah PK, Bora T. Role of environmental pollutants in liver physiology: special references to peoples living in the oil drilling sites of Assam. PloS one. 2015 Apr 13;10(4):e0123370.

  11. Gali-Muhtasib H, El-Najjar N, Schneider-Stock R. The medicinal potential of black seed (Nigella sativa) and its components. Advances in Phytomedicine. 2006 Jan 1;2:133-53.

  12. Ahmad MF, Ahmad FA, Ashraf SA, Saad HH, Wahab S, Khan MI, Ali M, Mohan S, Hakeem KR, Athar MT. An updated knowledge of Black seed (Nigella sativa Linn.): Review of phytochemical constituents and pharmacological properties. Journal of herbal medicine. 2021 Feb 1;25:100404.

  13. Al-Azzawi MA, AboZaid MM, Ibrahem RA, Sakr MA. Therapeutic effects of black seed oil supplementation on chronic obstructive pulmonary disease patients: A randomized controlled double blind clinical trial. Heliyon. 2020 Aug 1;6(8):e04711.

  14. Hussain DA, Hussain MM. Nigella sativa (black seed) is an effective herbal remedy for every disease except death-a Prophetic statement which modern scientists confirm unanimously: a review. Adv Med Plant Res. 2016 Apr;4(2):27-57.

  15. Mahboubi M. Natural therapeutic approach of Nigella sativa (Black seed) fixed oil in management 

  16. Halder S, Islam A, Muhit MA, Shill MC, Haider SS. Self-emulsifying drug delivery system of black seed oil with improved hypotriglyceridemic effect and enhanced hepatoprotective function. Journal of Functional Foods. 2021 Mar 1;78:104391.

  17. Danladi J, Abdulsalam A, Timbuak JA, Ahmed SA, Mairiga AA, Dahiru AU. Hepatoprotective effect of black seed (Nigella sativa) oil on carbon tetrachloride (ccl4) induced liver toxicity in adult wistar rats. J Dental Med Sci. 2013 Jan;4(3):56-62.

  18. Tavakkoli A, Ahmadi A, Razavi BM, Hosseinzadeh H. Black seed (Nigella sativa) and its constituent thymoquinone as an antidote or a protective agent against natural or chemical toxicities. Iranian journal of pharmaceutical research: IJPR. 2017;16(Suppl):2.

  19. Mohamed A, Waris HM, Ramadan H, Quereshi M, Kalra J. Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using thymoquinone-biomed 2009. Biomedical sciences instrumentation. 2009 Jan 1;45:274-9.

  20. Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. Review on clinical trials of black seed (Nigella sativa) and its active constituent, thymoquinone. Journal of pharmacopuncture. 2017 Sep;20(3):179.

  21. Abo El‐Magd NF, El‐Mesery M, El‐Karef A, El‐Shishtawy MM. Amelioration effect of black seed oil against high‐fat diet‐induced obesity in rats through Nrf2/HO‐1 pathway. Journal of Food Biochemistry. 2021 Apr;45(4):e13693.

  22. Sayeed MS, Shams T, Hossain SF, Rahman MR, Mostofa AG, Kadir MF, Mahmood S, Asaduzzaman M. Nigella sativa L. seeds modulate mood, anxiety and cognition in healthy adolescent males. Journal of Ethnopharmacology. 2014 Feb 27;152(1):156-62.


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